Developmental delays (DD) and congenital anomalies (CA) are prevalent yet often remain undiagnosed despite comprehensive genetic testing.This study aims to investigate the diagnostic yield of trio whole-genome sequencing (WGS) in children presenting with DD or CA who remained undiagnosed after previous genetic testing.A prospective cohort study was
For over 30 years, defects of the functional integrity of the sperm membrane, as evidenced by a low hypo-osmotic swelling test when evaluating the semen analysis, are not only associated with male infertility (even with sperm that otherwise seem normal), but unless corrected, successful intrauterine pregnancies will rarely ensue.This defect, intere
Abstract Background In most health areas, an information system is necessary for an effective fight against COVID-19.Current methods for surveillance of diseases with epidemic potential do not include monitoring the adherence to preventive measures.Furthermore, modern data collection methods depend often on technologies (e.g., cameras or drones) th
Osteochondral lesions that compromise the ankle are rare, with an incidence between 0.02% and 1.5% according to different series.This location is the third in frequency, after knee and elbow.The location of the osteochondral lesion allows one to infer the producing mechanism.Lateral defects are produced by Antihistamine inversion and dorsiflexion o
Introduction: Probiotic and postbiotic potential of thirty-two strains of lactic acid bacteria (LAB), obtained earlier from artisanal dairy sources in Pakistan, have been investigated against major multi-drug resistant (MDR) and food borne pathogenic bacteria.Methodology: LAB strains were identified by 16S rRNA gene sequencing and their antibacteri